Publications

MST-0312 Publications

MST-0312: FAP-targeted LTBR agonist induces High Endothelial Venules (HEV), lymphocyte infiltration and Tertiary Lymphoid Structures (TLS) in solid tumors

Lewandowska et al., Cancer Immunotherapy Keystone Symposia 2026 – available on request

Conditionally active, therapeutic lymphotoxin beta receptor (LTBR) agonist bispecific antibodies for induction of tertiary lymphoid structures in the treatment of solid tumors

Lewandowska et al., AACR Annual Meeting 2024 – available on request

Fibroblast and TLS Biology Publications

An immune cell map of human lung adenocarcinoma development reveals an anti-tumoral role of the Tfh-dependent tertiary lymphoid structure

Liu et al., Cell Reports Medicine 2024

Tertiary lymphoid structures in anticancer immunity

Teillaud et al., Nature Reviews Cancer 2024

Tertiary lymphoid structures and B cells determine clinically relevant T cell phenotypes in ovarian cancer

Kasikova et al., Nature Communications 2024

The cancer-immunity cycle: Indication, genotype, and immunotype

Mellman et al., Immunity 2023

High endothelial venules in cancer: Regulation, function, and therapeutic implication

Vella et al., Cancer Cell 2023

Antibodies against endogenous retroviruses promote lung cancer immunotherapy

Ng et al., Nature 2023

Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases

Korunsky et al. Med 2022

Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer

Meylan et al., Immunity 2022

Fibroblasts as immune regulators in infection, inflammation and cancer

Davidson et al. Nat Rev Immunol 2021

Notch signalling drives synovial fibroblast identity and arthritis pathology

Wei et al. Nature 2021

Mature tertiary lymphoid structures predict immune checkpoint inhibitor efficacy in solid tumors independently of PD-L1 expression

Vanhersecke et al. Nat Cancer 2021

A framework for advancing our understanding of cancer-associated fibroblasts

Sahai et al., Nat Rev Cancer 2020

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

Cabrita et al. Nature 2020

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

Elyada et al Cancer Discovery 2019

Distinct fibroblast subsets drive inflammation and damage in arthritis

Croft et al, Nature 2019